FeedbackThe manufacturer of our Estradiol assay has updated its standardization to the international reference method of isotope dilution gas chromatography mass spectrometry (ID-GCMS) method from the USP reference material. As a result, there are some changes to the reference ranges for patients as determined by the manufacturer.
| Current Ref Range | New Ref Range | |
|---|---|---|
| Males | 20-75 pg/mL | <48 pg/mL |
| Post-menopausal Females | 20-88 pg/mL | <41 pg/mL |
| Non-Pregnant Females: | ||
| Mid follicular phase | 24-114 pg/mL | 27-122 pg/mL |
| Mid luteal phase | 80-273 pg/mL | 49-291 pg/mL |
| Peri-ovulatory phase | 62-534 pg/mL | 95-433 pg/mL |
Reported values with this assay below 40 pg/mL must be interpreted with caution as the analytical variability (expressed as CV; coefficient of variation) remains >20% at these concentrations. If you would like further information, please call Linda Gaede (925) 692-5633, Pat Sinz (925) 692-5631, or me (925) 674-2508. Thank you.
