U.S. Aortic Stenosis Disease Prevalence & Treatment Statistics
- Heart disease is the leading cause of death in the U.S., killing more than 600,000 Americans each year.1
- More than five million Americans are diagnosed with heart valve disease each year.2
- Heart valve disease can occur in any single valve or a combination of the four valves, but diseases of the aortic and mitral valves are the most common.
- Calcific aortic stenosis is the most common cause of aortic stenosis (AS).3
- While up to 1.5 million people in the U.S. suffer from AS, approximately 500,000 within this group of patients suffer from severe AS. An estimated 250,000 patients with severe AS are symptomatic.4-6
- An echocardiogram (echo) is the primary imaging test used to diagnose severe AS.
- Without an aortic valve replacement (AVR), as many as 50 percent of patients with severe AS will not survive more than an average of two years after the onset of symptoms.7
- The predicted survival of inoperable patients with severe AS who are treated with standard non-surgical therapy is lower than with certain metastatic cancers.8